Clínica Fertia

What is Ovarian Hyperstimulation Syndrome?

Ovarian Hyperstimulation Syndrome, or OHSS, is a possible complication that can occur during IVF treatments. It is an abnormally elevated ovary response to hormonal medication that is usually administered in IVF patients to try to stimulate and increase the number of eggs for extraction and their subsequent fertilization.

Symptoms of Ovarian Hyperstimulation Syndrome

Ovarian Hyperstimulation Syndrome can range from mild, moderate, or severe cases. In mild cases it can lead to:

  • Enlargement of the ovaries.
  • Appearance of fluid, swelling, and mild pain in the abdomen.
  • Nausea or diarrhea.

In moderate or severe cases, other important complications may appear that may require hospital admission.

What causes OHSS?

Today we know that OHSS is produced as a consequence of the release of a series of vasoactive substances, at the level of the follicles after the administration of the hormone Chorionic Gonadotropin, the most important the vascular endothelial growth factor (VEGF). The vasoactive substances that are released induce the leakage of fluid and proteins from the intravascular space to the extravascular space, inducing hypotension, oliguria, presence of fluid in the abdomen and increased blood viscosity.

Can OHSS be avoided during IVF cycles?

At Clinica Fertia we have a personalized follow-up protocol for all our patients to avoid the development of this syndrome using various strategies such as, delayed transfer avoiding the use of Chorionic Gonadotropin to complete the maturation of the oocytes, using instead a Gn Rh analog, thus minimizing the risks to the maximum.

For more information contact our team to make your first appointment at our clinic.

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