Low ovarian reserve: causes, diagnosis and treatment in Málaga

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Have you been told that you have low ovarian reserve and don’t know what to do?

At Clínica Fertia in Málaga, we specialise in highly complex cases, such as low ovarian reserve.

  • A personalised assessment from your very first visit
  • Strategies tailored to your specific case
  • No waiting lists

We know what it means to be told that there are few eggs or that the response isn’t what you’d hoped for.

But we also know something important: every case is different and there’s room for action.

It’s not just about how many eggs there are, but how we work with them.

What is low ovarian reserve?

Low ovarian reserve refers to the reduced number of eggs retrieved following ovarian stimulation treatment.

According to ESHRE criteria, a low reserve is considered to be present when at least two of the following factors are met:

This is a common situation in assisted reproduction, but it requires a specialised approach.

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Causes of poor ovarian response

The most common cause is a decline in ovarian reserve with age, but it is not the only one.

Other causes may include:

Genetic factors

Endometriosis

Previous ovarian surgery

Chemotherapy or radiotherapy

Autoimmune diseases

Lifestyle (smoking, alcohol, toxins)

That is why it is essential to carry out a comprehensive assessment from the outset.

How can you tell if you have low ovarian reserve?

The diagnosis is made by means of:

At Clínica Fertia, we carry out a comprehensive assessment during the first visit.

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Treatment for low ovarian reserve at our fertility clinic

There is no single treatment. The key lies in designing a personalised strategy tailored to each patient.

At our unit, we use different approaches:

Personalised ovarian stimulation

We design tailored protocols:

  • Adjustment of medication and dosage
  • Use of pharmacogenetics
  • Intensive monitoring

Everyone’s body responds differently, which is why treatment cannot be standardised.

Embryo laboratory optimisation

We work with:

  • Embryo culture up to the blastocyst stage (day 5-6)
  • Advanced incubation systems (time-lapse)
  • Precise embryo selection


This allows us to maximise the potential of each embryo.

Endometrial preparation

We tailor the timing of the transfer:

  • Natural or substituted cycle
  • Endometrial assessment
  • Improving receptivity


Because it’s not just the embryo that matters, but also the timing.

Oocyte accumulation

In some cases, we plan several cycles to:

  • Obtain more oocytes
  • Generate more embryos
  • Increase the chances of success


A greater number of embryos are accumulated before a transfer is carried out.

Double ovarian stimulation (DuoStim)

We use advanced protocols such as DuoStim:

  • Two stimulations within a single cycle
  • Higher number of oocytes
  • Time optimisation


Particularly useful when time is a key factor.

Is it possible to achieve pregnancy with low ovarian reserve?

Yes. But it requires:

At Clínica Fertia, we treat these cases as highly complex, applying personalised reproductive medicine.

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Poor ovarian response at Clínica Fertia

If you’re looking for a fertility clinic in Málaga specialising in low ovarian reserve, at Clínica Fertia you’ll find:

We don’t treat cases, we treat people

Do you have concerns about your fertility or have you been diagnosed with low ovarian reserve?

At Clínica Fertia, your first fertility consultation is free

Frequently asked questions about low ovarian reserve

Does poor ovarian response mean infertility?

No. It means fewer eggs are retrieved, but it does not prevent pregnancy with the right strategy.

You cannot increase your ovarian reserve, but you can optimise your response and improve your chances.

AMH (anti-Müllerian hormone) measures ovarian reserve and helps predict response to treatment.

There is no exact number. In some cases, just a few good-quality eggs may be sufficient.

Yes, in some cases oocyte accumulation is carried out to increase the chances of success.

At Clínica Fertia, we have a unit specialising in complex cases.