Ovarian Hyperstimulation Syndrome, or OHSS, is a possible complication that can occur during IVF treatments.
It is an abnormally elevated ovarian response to hormonal medication that is usually administered to IVF patients to try to stimulate and increase the number of eggs for extraction and subsequent fertilization.
Symptoms of Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome can range from mild to moderate to severe. In mild cases it can lead to:
- Enlargement of the ovaries
- Appearance of fluid, swelling, and mild pain in the abdomen
- Nausea or diarrhea in mild cases
In moderate or severe cases, other important complications may appear that may require hospital admission.
What causes OHSS?
Today we know that OHSS occurs as a result of the release of a series of vasoactive substances at the level of the follicles, following the administration of the hormone human chorionic gonadotropin, the most important being vascular endothelial growth factor (VEGF).
The vasoactive substances that are released induce the leakage of fluid and proteins from the intravascular space to the extravascular space, causing hypotension, oliguria, fluid in the abdomen, and increased blood viscosity…
Can OHSS be avoided during IVF cycles?
At Fertia, we provide personalized follow-up for all our patients to help prevent the development of this syndrome, using various strategies such as delayed transfer, avoiding the use of human chorionic gonadotropin to complete oocyte maturation and using a GnRH analogue instead, thereby minimizing the risks as much as possible.
If you have any questions about your fertility treatment, contact us for your first free consultation.
