Coenzyme Q10, cellular energy and fertility: what is the connection?
Coenzyme Q10 (CoQ10) is a natural antioxidant essential for energy production within cells. Its role is especially important in tissues that consume a lot of energy, such as eggs and sperm.
With age —and in certain clinical profiles— CoQ10 levels decrease, which can affect reproductive capacity. That is why it is being researched as a support for women with low ovarian reserve, advanced age or low response to IVF.
How can CoQ10 help female fertility?
Improved egg quality in women with low reserve or advanced age
Scientific evidence indicates that CoQ10 can:
- Improve mitochondrial function in eggs.
- Protect against oxidative stress.
- Improve embryo quality in assisted reproduction treatments.
Recent studies have observed better fertilisation rates and higher-quality embryos in women who supplemented with CoQ10 before an IVF/ICSI cycle.
Does it increase pregnancy rates?
A meta-analysis shows an improvement in clinical pregnancy rates in women supplemented with CoQ10 in IVF/ICSI treatments.
However:
- It does not replace medical treatment.
- It does not guarantee live births.
Its benefits depend on the clinical profile.
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CoQ10 and male fertility: can it help?
In men, CoQ10 has also been shown to have benefits:
- It improves sperm motility.
- It reduces oxidative damage to DNA.
- It increases semen quality in cases of oligozoospermia or asthenozoospermia.
However, as in women, it has not been shown to improve pregnancy rates on its own.
Which type of CoQ10 is most effective?
- Ubiquinol vs ubiquinone
- Ubiquinol: active form, greater absorption.
- Ubiquinone: most common form, but less bioavailable.
The dosage and form should be prescribed by a specialist, especially in fertility treatments.
In what cases is CoQ10 recommended?
| Patient profile | Can you benefit? |
| Women over 35 years of age | Yes |
| Low ovarian reserve | Yes |
| FIV/ICSI | Yes, under supervision |
| Young women with good reserves | There is no clear evidence |
| Men with seminal disorders | Yes, as support |
Foods rich in CoQ10
- Red meat and poultry
- Oily fish: salmon, tuna
- Walnuts, almonds
- Spinach, broccoli
However, the levels used in studies cannot be achieved through diet alone, so supplementation is sometimes recommended.
When is CoQ10 NOT recommended?
- In young women without reproductive problems.
- As a substitute for medical treatment or diagnosis.
Without professional supervision.
Conclusion
Coenzyme Q10 can be an important ally, especially in women with low ovarian reserve or advanced age, and in men with seminal disorders.
It is not a magic solution, but it is a supplement based on growing scientific evidence.
🧡 Would you like to know if CoQ10 can help you?
Book an informative consultation at Clínica Fertia. Our team will assess your case and provide you with clear guidance.
