FISH (Fluorescent In Situ Hybridisation)
What is the FISH Technique?
To do this, the genetics laboratory performs a hybridization technique using DNA probes, with special affinity to certain chromosomes. The results must be analysed using equipment specially prepared to detect the fluorescence emitted by these probes.
Any cell in the human body has 23 pairs of chromosomes. However, gametes (eggs and sperm) to be chromosomally normal have to have half, that is, 23 chromosomes. If the division process, known as Meiosis, is not correct, the chromosomes are not distributed evenly and abnormal gametes will form. If an affected male gamete fertilizes a normal egg, the embryos will also carry this abnormality.