What is clomiphene citrate and what is it used for?
Introduction to clomiphene citrate
Clomiphene citrate is a widely used drug in fertility treatments, especially to stimulate ovulation in women who have difficulty ovulating. At Clínica Fertia, a center specialized in assisted reproduction, we use this medication in selected cases, such as women with polycystic ovary syndrome (PCOS) or anovulatory cycles.
How does clomiphene citrate work?
Clomiphene citrate acts on the brain by blocking estrogen receptors. This action causes the brain to interpret low levels of these hormones, stimulating the pituitary gland to release FSH (follicle-stimulating hormone) and LH (luteinizing hormone), which stimulate the ovaries, promoting:
- Ovarian follicle development
- Egg maturation
- Ovulation
It is administered orally for five days, usually starting between day 3 and 5 of the menstrual cycle. This treatment must always be supervised by a fertility specialist who will indicate the proper dosage and monitor the cycle with ultrasound scans.
How long does it take to get pregnant with clomiphene?
The response to clomiphene citrate may vary between women. In general:
- Ovulation usually occurs in the first months of treatment.
- Its use is not recommended beyond 6 cycles.
Factors that influence treatment success include:
- Age of the woman: Success rates are higher before age 35.
- Cause of infertility: It is more effective in cases of anovulation. It may not be suitable for women with tubal blockage or severe male factor infertility.
When is clomiphene citrate indicated?
This treatment is mainly indicated for:
- Women with irregular or anovulatory cycles
- Cases of polycystic ovary syndrome
- Unexplained infertility
Most common side effects
Clomiphene citrate is generally well tolerated, but mild side effects may occur, such as:
- Hot flashes
- Nausea
- Mood swings
- Abdominal discomfort
- Headaches
One of the risks is multiple pregnancy due to the ovulation of multiple eggs. Therefore, ultrasound monitoring of the treatment is essential to minimize this risk.
Conclusion
Clomiphene citrate is a simple and effective therapeutic option for young women with ovulation problems. At Clínica Fertia, we evaluate each case individually to offer the most appropriate treatment. Medical supervision is key to increasing success rates and minimizing potential risks.
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